Top Dental Supplement Startups
| Company | Location | Founded | Funding | Specialization | Key Products/Services |
|---|---|---|---|---|---|
| ProBiora Health | USA | N/A | N/A | Oral Probiotics | ProBiora3 patented formula (S. oralis, S. uberis, S. rattus), daily probiotic mints for teeth & gums |
| Hyperbiotics | USA | N/A | N/A | Oral Probiotics | PRO-Dental probiotic tablets with BLIS K12™ & M18™, chelated zinc for oral health |
| BURST Oral Care | USA | N/A | N/A | Oral Probiotics | Oral probiotics with 6 billion CFU, contains BLIS K12 & M18 strains |
| SuperTeeth | USA | N/A | N/A | Dental Probiotics | Mint-flavored dental probiotics with hydroxyapatite, targets oral microbiome |
| StellaLife | USA | N/A | N/A | Oral & Gut Probiotics | Pre+Post+Probiotic Kit (30-day supply), 27B CFU oral lozenges, 17.5B CFU gut capsules |
| Codeage | USA | N/A | N/A | Teeth & Gum Vitamins | Comprehensive vitamin supplement with calcium, collagen, vitamins A/C/D3/K2, oral probiotics |
| Biocidin Botanicals | USA | N/A | N/A | Oral Probiotics | Dentalflora® dissolvable tablets with BLIS M18®, 5B CFU at manufacture |
| Life Extension | USA | 1980 | N/A | Oral Health Supplements | Oral probiotics & dental supplements, 40+ years of research-backed formulations |
| ZERObrush | California, USA | N/A | $10.8M (Series A, 2025) | Automated Oral Care | Fully automated custom-fit oral cleaning device, advanced oral care technology |
| Floe Oral Care | London, UK | 2019 | N/A | AI Diagnostics | Machine learning with salivary diagnostics for oral health monitoring |
| Trek Gum | USA | N/A | N/A | Functional Gum | Plant-based “functional” chewing gum engineered to clean teeth |
| ORACURA | USA | N/A | N/A | Oral Care Innovation | Next-Gen oral care products using innovative technologies |
| Proclaim | USA | N/A | $15M | Automated Oral Care | Personalized automated oral care system with hydro station technology |
Key Trends in Dental Supplement Market:
The oral-care probiotic market in the United States has experienced exponential expansion, with more than 25 companies marketing probiotic products for oral health containing over 50 bacterial species and strains. The most common probiotic strains include:
Popular Probiotic Strains:
- Streptococcus salivarius (BLIS K12™ and M18™)
- Lactobacillus reuteri
- Lactobacillus paracasei
- Lactobacillus salivarius
Key Focus Areas:
- Oral Probiotics: Supporting oral microbiome balance, reducing bad breath, preventing cavities
- Vitamin Supplements: Calcium, Vitamin D, C, K2 for teeth and gum health
- Natural Solutions: Plant-based, allergen-free, GMO-free formulations
- Preventive Care: Early detection and prevention of dental issues
Note: Many established oral health supplement companies don’t publicly disclose detailed funding information as they operate as private companies or have been established for many years. The oral probiotic market is rapidly growing with increasing focus on preventive dental care and microbiome health.